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Combining functional mushrooms and microdosing: The ultimate guide
2 min read

Combining functional mushrooms and microdosing: The ultimate guide

Why combining mushrooms is the ultimate power move.

Combining Mabel’s Manna blends with truffles is not just a great idea, it’s an intentional, powerful way to enhance your mental and physical well-being. The synergy between the functional mushrooms and psilocybin microdosing creates what’s called an “entourage effect,” where each component amplifies the effects of the others. This is the very reason we created the Radical Wellbeing Set, combining Morning Manna, Midnight Manna, and Mindful Microdosing for a full-circle wellness experience.

The science behind stacking: The entourage effect

When you combine functional mushrooms with psilocybin, you’re tapping into a phenomenon where the sum is greater than its parts. Each mushroom targets a specific area of mental, physical, or emotional health, and when paired with psilocybin, the effects are amplified.

One of the most remarkable combinations is Lion’s Mane + Psilocybin, known for promoting neurogenesis. This combo helps the brain regenerate, rewire, and become more adaptable, which is crucial as we age and face stress.

Product pairings: How to use Manna blends with truffles 

Morning Manna + Microdosing: Clarity & cognitive support
  • Lion’s Mane: Enhances neurogenesis, helping to “rewire” the brain and improve memory, emotional resilience, and cognitive flexibility.

  • Cordyceps: Boosts natural energy, helping you feel alert and physically vital without a crash.

Midnight Manna + Microdosing: Restoration & emotional grounding
  • Reishi: Supports emotional balance, serotonin production, and deep, restorative sleep.

  • Chaga: Aids in stress management, antioxidant support, and nervous system regulation.

Why this combo works

The combination of Manna blends with microdosing supports a natural rhythm that nourishes the brain and body throughout the day. You get morning clarity, evening calm, and ongoing support for stress regulation, neuroplasticity, and restorative sleep.

Practical tips for daily use

  1. Follow the recommended dosing schedule: Morning Manna and truffles in the AM, Midnight Manna in the PM.

  2. Take it slow: Start with small doses to gauge how your body responds.

  3. Keep a journal: Track how you feel after each combination to fine-tune your routine. 

Conclusion

By intentionally combining Manna blends with microdosing, you’re not just supplementing, you’re building a holistic routine that supports long-term well-being. Feel free to experiment within safe limits, and let us know how it goes! Your journey to radical wellness starts here.